BEST1
bestrophin 1
同義詞:
ARB, BEST, BMD, RP50, TU15B, VMD2
物種:
Human BEST1 (7439), Mouse Best1 (24115), Rat Best1 (293735), fruit fly Best1 (53431), cow BEST1 (508924), Horse BEST1 (100059901), dog BEST1 (483791), domestic cat BEST1 (101084904), chicken BEST1 (423124), naked mole-rat Best1 (101710606) ...更多
UniProtKB ID:
基因 ID:
- Human(7439) Summary: This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008]
- Mouse(24115) bestrophin 1
- Rat(293735) bestrophin 1
- fruit fly(53431) Bestrophin 1
- cow(508924) bestrophin 1
- Horse(100059901) bestrophin 1
- dog(483791) bestrophin 1
- domestic cat(101084904) bestrophin 1
- chicken(423124) bestrophin 1
- naked mole-rat(101710606) bestrophin 1
- domestic guinea pig(100723621) bestrophin 1
- sheep(101109837) bestrophin 1
- Domestic Rabbit(100352203) bestrophin 1
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Antibodies
產品編號
描述
物種活性
應用
Anti-Bestrophin Antibody, Chemicon®, from mouse,
物種活性
bovine, human, monkey, mouse, pig
應用
immunohistochemistry
western blot
western blot