ATM
ataxia telangiectasia mutated
同義詞:
AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1
物種:
Human ATM (472), Mouse Atm (11920), Rat Atm (300711), Zebrafish atm (403064), cow ATM (526824), Horse ATM (100061765), domestic cat ATM (101089291), dog ATM (479450), chicken ATM (395401), Thale Cress ATM (823975) ...更多
UniProtKB ID:
基因 ID:
- Human(472) Summary: The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]
- Mouse(11920) ataxia telangiectasia mutated homolog (human)
- Rat(300711) ataxia telangiectasia mutated
- Zebrafish(403064) ataxia telangiectasia mutated
- cow(526824) ataxia telangiectasia mutated
- Horse(100061765) ataxia telangiectasia mutated
- domestic cat(101089291) ataxia telangiectasia mutated
- dog(479450) ataxia telangiectasia mutated
- chicken(395401) ataxia telangiectasia mutated
- Thale Cress(823975) serine/threonine-protein kinase ATM
- naked mole-rat(101718948) ataxia telangiectasia mutated
- domestic guinea pig(100717983) ataxia telangiectasia mutated
- sheep(101105847) ataxia telangiectasia mutated
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Antibodies
產品編號
描述
物種活性
應用
抗磷酸ATM（Ser1981）抗体，克隆10H11.E12, clone 10H11.E12, Upstate®, from mouse,
物種活性
human, mouse
應用
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
immunofluorescence
immunoprecipitation (IP)
western blot
抗-ATM 磷酸化Ser1981抗体（克隆10H11.E12）, clone 10H11.E12, Chemicon®, from mouse,
物種活性
human, mouse
應用
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-phospho-ATM (Ser1981) Antibody, clone 10H11.E12 PE conjugate, clone 10H11.E12, from mouse, PE,
物種活性
human, mouse, rat
應用
flow cytometry
Anti-phospho-ATM (Ser1981) Antibody, clone 10H11.E12, Alexa Fluor™ 488, clone 10H11.E12, from mouse, ALEXA FLUOR™ 488,
物種活性
human, mouse
應用
immunocytochemistry
Proteins
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描述
物種
esiRNA
產品編號
描述
物種