ARHGAP8
Rho GTPase activating protein 8
同義詞:
BPGAP1, PP610
物種:
Human ARHGAP8 (23779), Mouse Arhgap8 (73167), Rat Arhgap8 (300115), naked mole-rat Arhgap8 (101703941), domestic guinea pig Arhgap8 (100723032), chicken ARHGAP8 (418239), dog ARHGAP8 (100533462), domestic cat ARHGAP8 (101094114)
UniProtKB ID:
基因 ID:
- Human(23779) Summary: This gene encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq, Nov 2010]
- Mouse(73167) Rho GTPase activating protein 8
- Rat(300115) Rho GTPase activating protein 8
- naked mole-rat(101703941) Rho GTPase activating protein 8
- domestic guinea pig(100723032) Rho GTPase activating protein 8
- chicken(418239) Rho GTPase activating protein 8
- dog(100533462) Rho GTPase activating protein 8
- domestic cat(101094114) Rho GTPase activating protein 8
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