APC
adenomatous polyposis coli
同義詞:
BTPS2, DP2, DP2.5, DP3, GS, PPP1R46
物種:
Human APC (324), Mouse Apc (11789), Rat Apc (24205), sheep APC (101104664), domestic guinea pig Apc (100723694), naked mole-rat Apc (101704055), Zebrafish apc (386762), fruit fly Apc (44642), cow APC (533233), Horse APC (100064431) ...更多
UniProtKB ID:
基因 ID:
- Human(324) Summary: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]
- Mouse(11789) adenomatosis polyposis coli
- Rat(24205) adenomatous polyposis coli
- sheep(101104664) adenomatous polyposis coli
- domestic guinea pig(100723694) adenomatous polyposis coli
- naked mole-rat(101704055) adenomatous polyposis coli
- Zebrafish(386762) adenomatosis polyposis coli
- fruit fly(44642) APC-like
- cow(533233) adenomatous polyposis coli
- Horse(100064431) adenomatous polyposis coli
- domestic cat(101096138) adenomatous polyposis coli
- dog(479139) adenomatous polyposis coli
- chicken(415607) adenomatous polyposis coli
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Antibodies
產品編號
描述
物種活性
應用
Anti-APC antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-APC (C-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
物種活性
human
應用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-APC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物種活性
human
應用
immunohistochemistry
Anti-APC antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
proximity ligation assay
western blot
western blot