ADRA1B
adrenoceptor alpha 1B
同義詞:
ADRA1, ALPHA1BAR
物種:
Human ADRA1B (147), Mouse Adra1b (11548), Rat Adra1b (24173), chicken ADRA1B (373890), domestic cat ADRA1B (101092238), cow ADRA1B (407140), dog ADRA1B (403962), domestic guinea pig Adra1b (100735480), sheep ADRA1B (101114869), Domestic Rabbit ADRA1B (100008731)
UniProtKB ID:
基因 ID:
- Human(147) Summary: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq, Jul 2008]
- Mouse(11548) adrenergic receptor, alpha 1b
- Rat(24173) adrenoceptor alpha 1B
- chicken(373890) adrenergic, alpha-1B-, receptor
- domestic cat(101092238) adrenoceptor alpha 1B
- cow(407140) adrenergic, alpha-1B-, receptor
- dog(403962) adrenoceptor alpha 1B
- domestic guinea pig(100735480) adrenoceptor alpha 1B
- sheep(101114869) adrenoceptor alpha 1B
- Domestic Rabbit(100008731) adrenoceptor alpha 1B
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