ACVR2B
activin A receptor, type IIB
同義詞:
ACTRIIB, ActR-IIB, HTX4
物種:
Human ACVR2B (93), Mouse Acvr2b (11481), Rat Acvr2b (25366), Zebrafish acvr2b (30457), dog ACVR2B (485590), cow ACVR2B (282131), Horse ACVR2B (100053588), domestic cat ACVR2B (101086087), chicken ACVR2B (374213), naked mole-rat Acvr2b (101711703) ...更多
UniProtKB ID:
基因 ID:
- Human(93) Summary: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq, Jul 2008]
- Mouse(11481) activin receptor IIB
- Rat(25366) activin A receptor, type IIB
- Zebrafish(30457) activin receptor IIb
- dog(485590) activin A receptor, type IIB
- cow(282131) activin A receptor, type IIB
- Horse(100053588) activin A receptor, type IIB
- domestic cat(101086087) activin A receptor, type IIB
- chicken(374213) activin A receptor, type IIB
- naked mole-rat(101711703) activin A receptor, type IIB
- domestic guinea pig(100722791) activin A receptor, type IIB
- sheep(443156) activin A receptor, type IIB
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
產品編號
描述
物種活性
應用
Anti-Activin Receptor IIB antibody produced in goat, affinity isolated antibody,
物種活性
human
應用
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ACVR2B antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, guinea pig, horse, human, rat, sheep
應用
western blot
Monoclonal Anti-ACVR2B antibody produced in mouse, clone 1C11, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot
western blot
Anti-ACVR2B antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, guinea pig, horse, human, mouse, rat, sheep
應用
western blot