ACLY
ATP citrate lyase
同義詞:
ACL, ATPCL, CLATP
物種:
Human ACLY (47), Mouse Acly (104112), Rat Acly (24159), chicken ACLY (395373), Horse ACLY (100053195), cow ACLY (511135), domestic cat ACLY (100422779), dog ACLY (607852), naked mole-rat Acly (101700349), domestic guinea pig Acly (100714933)
UniProtKB ID:
基因 ID:
- Human(47) Summary: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(104112) ATP citrate lyase
- Rat(24159) ATP citrate lyase
- chicken(395373) ATP citrate lyase
- Horse(100053195) ATP citrate lyase
- cow(511135) ATP citrate lyase
- domestic cat(100422779) ATP citrate lyase
- dog(607852) ATP citrate lyase
- naked mole-rat(101700349) ATP citrate lyase
- domestic guinea pig(100714933) ATP citrate lyase
- sheep(654404) ATP citrate lyase
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Antibodies
Product Number
描述
物種活性
應用
Anti-ATP-citrate synthase/ACLY Antibody, from rabbit, purified by affinity chromatography,
物種活性
bovine, human, mouse, porcine, rat, sheep
應用
immunohistochemistry
western blot
western blot
Anti-phospho-ATP-Citrate Lyase (pSer454) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ATP-Citrate Lyase antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
western blot
western blot
Proteins
Product Number
描述
物種