跳轉至內容
Merck

ACLY

ATP citrate lyase

同義詞:
ACL, ATPCL, CLATP
物種:
UniProtKB ID:
基因 ID:
  • Human(47) Summary: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(104112) ATP citrate lyase
  • Rat(24159) ATP citrate lyase
  • chicken(395373) ATP citrate lyase
  • Horse(100053195) ATP citrate lyase
  • cow(511135) ATP citrate lyase
  • domestic cat(100422779) ATP citrate lyase
  • dog(607852) ATP citrate lyase
  • naked mole-rat(101700349) ATP citrate lyase
  • domestic guinea pig(100714933) ATP citrate lyase
  • sheep(654404) ATP citrate lyase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

產品編號
描述
物種活性
應用
Anti-ATP-citrate synthase/ACLY Antibody, from rabbit, purified by affinity chromatography,
物種活性
bovine, human, mouse, porcine, rat, sheep
應用
immunohistochemistry
western blot
Anti-phospho-ATP-Citrate Lyase (pSer454) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry

western blot
Anti-ATP-Citrate Lyase antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
western blot

Proteins

產品編號
描述
物種
ATP枸橼酸裂解酶活性 人, recombinant, expressed in baculovirus, ≥90% (SDS-PAGE),
物種
human