ABI1
abl-interactor 1
同義詞:
ABI-1, ABLBP4, E3B1, NAP1BP, SSH3BP, SSH3BP1
物種:
Human ABI1 (10006), Mouse Abi1 (11308), Rat Abi1 (79249), Thale Cress ABI1 (828714), dog ABI1 (607247), Horse ABI1 (100055377), cow ABI1 (540815), domestic cat ABI1 (101082922), chicken ABI1 (420489), naked mole-rat Abi1 (101724965) ...更多
UniProtKB ID:
基因 ID:
- Human(10006) Summary: This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011]
- Mouse(11308) abl-interactor 1
- Rat(79249) abl-interactor 1
- Thale Cress(828714) protein phosphatase 2C 56
- dog(607247) abl-interactor 1
- Horse(100055377) abl-interactor 1
- cow(540815) abl-interactor 1
- domestic cat(101082922) abl-interactor 1
- chicken(420489) abl-interactor 1
- naked mole-rat(101724965) abl-interactor 1
- domestic guinea pig(100720396) abl-interactor 1
- Domestic Rabbit(100349265) abl-interactor 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
產品編號
描述
物種活性
應用
Anti-phospho-Abi-1 (Ser225) Antibody, from rabbit, purified by affinity chromatography,
物種活性
human, monkey, mouse, rat
應用
western blot
Anti-phospho-Abl (Tyr412) Antibody, Upstate®, from rabbit,
物種活性
human, mouse, rat
應用
ELISA
western blot
western blot
Anti-ABI1 兔抗, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
物種活性
canine, human, mouse, rat
應用
western blot
Anti-phospho-Abl (Tyr245) Antibody, Upstate®, from rabbit,
物種活性
human, mouse, rat
應用
ELISA
western blot
western blot