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Merck

Lanthanum(III) triflate catalyzed direct amidation of esters.

Organic letters (2014-03-26)
Hiroyuki Morimoto, Risa Fujiwara, Yuhei Shimizu, Kazuhiro Morisaki, Takashi Ohshima
PMID24660939
ABSTRACT

Lanthanum trifluoromethanesulfonate is an effective single-component catalyst for synthesizing a variety of amides directly from esters and amines under mild conditions. Highly selective amidation of esters and amines, as well as catalyst-controlled amidation of esters, demonstrated the effectiveness of the catalyst system.

MATERIALS
Product Number
Brand
Product Description
263109
Sigma-Aldrich
Lanthanum, powder, −40 mesh, under oil, 99.9% trace rare earth metals basis
263117
Sigma-Aldrich
Lanthanum, pieces
GF13609111
Lanthanum, foil, 25x25mm, thickness 0.125mm, as rolled, 99%
531197
Sigma-Aldrich
Ethyl 6-chloropyridine-3-carboxylate, 97%