S7920

Sodium fluoride

BioXtra, ≥99%

• Synonym(s): NaF, Natrium fluoride, Sodium monoflouride
• Linear Formula: NaF
• CAS Number: 7681-49-4
• Molecular Weight: 41.99
• EC Number: 231-667-8
• MDL number: MFCD00003524
• UNSPSC Code: 12352302
• PubChem Substance ID: 24899770
• NACRES: NA.25

Properties

• vapor pressure: 1.4 mmHg ( 0 °C)
• Quality Level: 200
• product line: BioXtra
• Assay: ≥99%
• impurities: ≤0.0005% Phosphorus (P); ≤0.1% Insoluble matter
• mp: 993 °C (lit.)
• solubility: H₂O: 1 M, clear, colorless
• anion traces: chloride (Cl^-): ≤0.005%; sulfate (SO₄^2-): ≤0.03%
• cation traces: Al: ≤0.001%; Ca: ≤0.0005%; Cu: ≤0.0005%; Fe: ≤0.003%; K: ≤0.02%; Mg: ≤0.0005%; NH₄⁺: ≤0.1%; Pb: ≤0.001%; Zn: ≤0.0005%
• SMILES string: [F-].[Na+]
• InChI: 1S/FH.Na/h1H;/q;+1/p-1
• InChI key: PUZPDOWCWNUUKD-UHFFFAOYSA-M

Description

Application

Sodium fluoride has been used:

• as a source of fluoride ions, to analyse its impact on spermatogenesis and capacitation in vitro
• as an additive in the extraction buffer for the isolation of nuclei, cytoplasmic and nuclear proteins
• as a component of lysis buffer for the lysis of human ovarian adenocarcinoma OVCAR3 cells

Biochem/physiol Actions

Sodium fluoride (NaF) prevents dental caries, by catalysing the diffusion of calcium and phosphate and remineralizes the lesions. Fluoride affects spermatogenesis and capacitation process in the female reproductive tract. Fluoride induces oxidative stress, DNA damage in ovary ultimately affects the development of oocytes. Fluoride supplementation enhances bone mineral density. 18F-NaF is a radiotracer used in positron emission tomography (PET) to identify atherosclerotic lesions and other cardiac plaques.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301 - H315 - H319
• Precautionary Statements: P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Supplementary Hazards: EUH032
• Storage Class Code: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves