D44804

α,α′-Dibromo-p-xylene

97%

• Synonym(s): 1,4-Bis(bromomethyl)benzene, p-Xylylene dibromide
• Linear Formula: C₆H₄(CH₂Br)₂
• CAS Number: 623-24-5
• Molecular Weight: 263.96
• Beilstein: 1100019
• EC Number: 210-781-1
• MDL number: MFCD00000182
• UNSPSC Code: 12352100
• PubChem Substance ID: 24893876
• NACRES: NA.22

Properties

• Assay: 97%
• form: crystals
• bp: 245 °C (lit.)
• mp: 143-145 °C (lit.)
• SMILES string: BrCc1ccc(CBr)cc1
• InChI: 1S/C8H8Br2/c9-5-7-1-2-8(6-10)4-3-7/h1-4H,5-6H2
• InChI key: RBZMSGOBSOCYHR-UHFFFAOYSA-N

Description

Application

α,α′-Dibromo-p-xylene can be used as a building block to synthesize:      

• Phthalazinone derivatives, which are reported as potent inhibitors of phosphodiesterase 4.    
• N-Phenylated polyamine via polycondensation reaction with aniline and α, α′-dianilino-p-xylene.     
• Porous polymeric network (PPN) via a Friedel-Crafts alkylation reaction with triphenylamine using FeCl₃ as an oxidizing agent.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves