TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
Synonyms:
OCIF, OPG, TR1
Species:
Human TNFRSF11B (4982), Mouse Tnfrsf11b (18383), Rat Tnfrsf11b (25341), Zebrafish tnfrsf11b (407674), dog TNFRSF11B (482025), Horse TNFRSF11B (100065885), domestic cat TNFRSF11B (101096878), chicken TNFRSF11B (378803), domestic guinea pig Tnfrsf11b (100715850), Domestic Rabbit TNFRSF11B (100348133) ...More
UniProtKB ID:
Gene ID:
- Human(4982) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
- Mouse(18383) tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
- Rat(25341) tumor necrosis factor receptor superfamily, member 11b
- Zebrafish(407674) tumor necrosis factor receptor superfamily, member 11b
- dog(482025) tumor necrosis factor receptor superfamily, member 11b
- Horse(100065885) tumor necrosis factor receptor superfamily, member 11b
- domestic cat(101096878) tumor necrosis factor receptor superfamily, member 11b
- chicken(378803) tumor necrosis factor receptor superfamily, member 11b
- domestic guinea pig(100715850) tumor necrosis factor receptor superfamily, member 11b
- Domestic Rabbit(100348133) tumor necrosis factor receptor superfamily, member 11b
- naked mole-rat(101709512) tumor necrosis factor receptor superfamily, member 11b
- cow(523822) tumor necrosis factor receptor superfamily, member 11b
- Goat(100860896) tumor necrosis factor receptor superfamily, member 11b
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ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Osteoprotegerin/TNFRSF11B Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-Osteoprotegerin antibody produced in goat, affinity isolated antibody, lyophilized powder,
Species Reactivity
mouse
Application
immunohistochemistry
neutralization
western blot
neutralization
western blot
Anti-TNFRSF11B antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Proteins
Product Number
Description
Species
Osteoprotegerin/Fc Chimera from mouse, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
mouse
Osteoprotegerin (OPG) human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human