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Merck

SLC9A3R1

solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1

Synonyms:
EBP50, NHERF, NHERF-1, NHERF1, NPHLOP2
Species:
UniProtKB ID:
Gene ID:
  • Human(9368) Summary: This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq, Sep 2009]
  • Mouse(26941) solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
  • Rat(59114) solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
  • Zebrafish(327272) solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
  • dog(483299) solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
  • domestic cat(101091236) solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
  • chicken(422108) solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
  • cow(505242) solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
  • sheep(780527) solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
  • naked mole-rat(101697195) solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
  • Domestic Rabbit(100009196) solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
  • domestic guinea pig(100724451) solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Ezrin (Thr567)/Radixin (Thr564)/Moesin (Thr558) Antibody, phospho-specific, Chemicon®, from rabbit,
Species Reactivity
human, monkey, mouse, rat
Application
immunohistochemistry
western blot
Anti-Ezrin/Radixin/Moesin Antibody, Chemicon®, from rabbit,
Species Reactivity
human, monkey, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot