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Merck

SLC29A1

solute carrier family 29 (equilibrative nucleoside transporter), member 1

Synonyms:
ENT1
Species:
UniProtKB ID:
Gene ID:
  • Human(2030) Summary: This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(63959) solute carrier family 29 (nucleoside transporters), member 1
  • Rat(63997) solute carrier family 29 (equilibrative nucleoside transporter), member 1
  • cow(510932) solute carrier family 29 (nucleoside transporters), member 1
  • sheep(101117541) solute carrier family 29 (nucleoside transporters), member 1
  • Goat(100861005) solute carrier family 29 (nucleoside transporters), member 1
  • Domestic Rabbit(100357908) solute carrier family 29 (nucleoside transporters), member 1
  • naked mole-rat(101701245) solute carrier family 29 (nucleoside transporters), member 1
  • domestic guinea pig(100730207) solute carrier family 29 (nucleoside transporters), member 1
  • chicken(421439) solute carrier family 29 (nucleoside transporters), member 1
  • Horse(100055498) solute carrier family 29 (nucleoside transporters), member 1
  • dog(442966) solute carrier family 29 (nucleoside transporters), member 1
  • domestic cat(101095579) solute carrier family 29 (nucleoside transporters), member 1

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Small Molecule - Antagonist

Product Number
Description
Species
2′-Deoxyuridine, ≥98.5%,
Species
mouse
3′-Azido-3′-deoxythymidine, ≥98% (HPLC),
Species
mouse
S-(4-Nitrobenzyl)-6-thioinosine, ≥98%, solid,
Species
human
Dipyridamole, ≥98% (HPLC),
Species
mouse, human

Antibodies

Product Number
Description
Species Reactivity
Application
ANTI-ENT1(C-TERMINAL) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-HENT1 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP120, affinity isolated antibody,
Species Reactivity
human, rabbit, rat
Application
immunohistochemistry

Small Molecule - Inhibitor

Product Number
Description
Species
3′-Azido-3′-deoxythymidine, ≥98% (HPLC),
Species
mouse
S-(4-Nitrobenzyl)-6-thioinosine, ≥98%, solid,
Species
human
Dipyridamole for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Dipyridamole, British Pharmacopoeia (BP) Reference Standard,
Species
human
Dipyridamole, European Pharmacopoeia (EP) Reference Standard,
Species
human