SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
Synonyms:
ACSVL1, FACVL1, FATP2, HsT17226, VLACS, VLCS, hFACVL1
Species:
Human SLC27A2 (11001), Mouse Slc27a2 (26458), Rat Slc27a2 (65192), chicken SLC27A2 (426354), dog SLC27A2 (478298), Horse SLC27A2 (100069953), domestic cat SLC27A2 (101096897), cow SLC27A2 (535727), sheep SLC27A2 (101108576), naked mole-rat Slc27a2 (101712294) ...More
UniProtKB ID:
Gene ID:
- Human(11001) Summary: The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]
- Mouse(26458) solute carrier family 27 (fatty acid transporter), member 2
- Rat(65192) solute carrier family 27 (fatty acid transporter), member 2
- chicken(426354) solute carrier family 27 (fatty acid transporter), member 2
- dog(478298) solute carrier family 27 (fatty acid transporter), member 2
- Horse(100069953) solute carrier family 27 (fatty acid transporter), member 2
- domestic cat(101096897) solute carrier family 27 (fatty acid transporter), member 2
- cow(535727) solute carrier family 27 (fatty acid transporter), member 2
- sheep(101108576) solute carrier family 27 (fatty acid transporter), member 2
- naked mole-rat(101712294) solute carrier family 27 (fatty acid transporter), member 2
- Domestic Rabbit(100352860) solute carrier family 27 (fatty acid transporter), member 2
- domestic guinea pig(100719516) solute carrier family 27 (fatty acid transporter), member 2
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