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Merck

SEMA3A

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

Synonyms:
COLL1, HH16, Hsema-I, Hsema-III, SEMA1, SEMAD, SEMAIII, SEMAL, SemD, coll-1
Species:
Human SEMA3A (10371), Mouse Sema3a (20346), Rat Sema3a (29751), chicken SEMA3A (395825), domestic cat SEMA3A (101094836), dog SEMA3A (483386), domestic guinea pig Sema3a (100731288), cow SEMA3A (537777), sheep SEMA3A (101113580)
UniProtKB ID:
Q14563
Gene ID:
  • Human(10371) Summary: This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease. [provided by RefSeq, Jul 2008]
  • Mouse(20346) sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
  • Rat(29751) sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
  • chicken(395825) sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
  • domestic cat(101094836) sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
  • dog(483386) sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
  • domestic guinea pig(100731288) sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
  • cow(537777) sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
  • sheep(101113580) sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

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Antibodies

Product Number
Description
Species Reactivity
Application
WH0010371M1
Monoclonal Anti-SEMA3A antibody produced in mouse, clone 5G9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
AB9604
Anti-Semaphorin 3A Antibody, central region, Chemicon®, from rabbit,
Species Reactivity
human, rat
Application
western blot
MABN783
Anti-Semaphorin 3A Antibody, clone Sema-3A, clone Sema-3A, from mouse,
Species Reactivity
chicken, fish, human, mouse, rabbit, rat
Application
immunofluorescence
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EHU021581
MISSION® esiRNA, targeting human SEMA3A,
Species
human
EMU018631
MISSION® esiRNA, targeting mouse Sema3a,
Species
mouse