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Merck

RFXANK

regulatory factor X-associated ankyrin-containing protein

Synonyms:
ANKRA1, BLS, F14150_1, RFX-B
Species:
Human RFXANK (8625), Mouse Rfxank (19727), Rat Rfxank (306353), cow RFXANK (100125917), sheep RFXANK (101105568), naked mole-rat Rfxank (101712628), domestic guinea pig Rfxank (100716895), Zebrafish rfxank (100170804), domestic cat RFXANK (101098525), dog RFXANK (476662)
UniProtKB ID:
O14593, O95839, Q6FGA8
Gene ID:
  • Human(8625) Summary: Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2013]
  • Mouse(19727) regulatory factor X-associated ankyrin-containing protein
  • Rat(306353) regulatory factor X-associated ankyrin-containing protein
  • cow(100125917) regulatory factor X-associated ankyrin-containing protein
  • sheep(101105568) regulatory factor X-associated ankyrin-containing protein
  • naked mole-rat(101712628) regulatory factor X-associated ankyrin-containing protein
  • domestic guinea pig(100716895) regulatory factor X-associated ankyrin-containing protein
  • Zebrafish(100170804) regulatory factor X-associated ankyrin-containing protein
  • domestic cat(101098525) regulatory factor X-associated ankyrin-containing protein
  • dog(476662) regulatory factor X-associated ankyrin-containing protein
  • chicken(426623) regulatory factor X-associated ankyrin-containing protein

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB1411547
Anti-RFXANK antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot