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Merck

RBFOX1

RNA binding protein, fox-1 homolog (C. elegans) 1

Synonyms:
2BP1, A2BP1, FOX-1, FOX1, HRNBP1
Species:
Human RBFOX1 (54715), Mouse Rbfox1 (268859), Rat Rbfox1 (302920), Zebrafish rbfox1 (449554), Horse RBFOX1 (100066233), domestic cat RBFOX1 (101089565), dog RBFOX1 (609116), chicken RBFOX1 (416645), domestic guinea pig Rbfox1 (100723769), naked mole-rat Rbfox1 (101707083) ...More
UniProtKB ID:
Q9NWB1, Q7Z7I7, Q8TAE3, Q8TAF2, Q8WYB2, Q9NS20
Gene ID:
  • Human(54715) Summary: The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  • Mouse(268859) RNA binding protein, fox-1 homolog (C. elegans) 1
  • Rat(302920) RNA binding protein, fox-1 homolog (C. elegans) 1
  • Zebrafish(449554) RNA binding protein, fox-1 homolog (C. elegans) 1
  • Horse(100066233) RNA binding protein, fox-1 homolog (C. elegans) 1
  • domestic cat(101089565) RNA binding protein, fox-1 homolog (C. elegans) 1
  • dog(609116) RNA binding protein, fox-1 homolog (C. elegans) 1
  • chicken(416645) RNA binding protein, fox-1 homolog (C. elegans) 1
  • domestic guinea pig(100723769) RNA binding protein, fox-1 homolog (C. elegans) 1
  • naked mole-rat(101707083) RNA binding protein, fox-1 homolog (C. elegans) 1
  • cow(521304) RNA binding protein, fox-1 homolog (C. elegans) 1
  • sheep(101105300) RNA binding protein, fox-1 homolog (C. elegans) 1

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Antibodies

Product Number
Description
Species Reactivity
Application
MABE960
Anti-Fox1 Antibody, clone A2BP1, clone A2BP1, from rat,
Species Reactivity
human, mouse
Application
immunocytochemistry
immunofluorescence
immunohistochemistry