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Merck

RARA

retinoic acid receptor, alpha

Synonyms:
NR1B1, RAR
Species:
Human RARA (5914), Mouse Rara (19401), Rat Rara (24705), chicken RARA (395213), dog RARA (480526), domestic cat RARA (101083048), domestic guinea pig Rara (100728220), naked mole-rat Rara (101722948), cow RARA (534280)
UniProtKB ID:
P10276, B8Y636, P78456, Q13440, Q13441, Q96S41, Q9NQS0
Gene ID:
  • Human(5914) Summary: This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010]
  • Mouse(19401) retinoic acid receptor, alpha
  • Rat(24705) retinoic acid receptor, alpha
  • chicken(395213) retinoic acid receptor, alpha
  • dog(480526) retinoic acid receptor, alpha
  • domestic cat(101083048) retinoic acid receptor, alpha
  • domestic guinea pig(100728220) retinoic acid receptor, alpha
  • naked mole-rat(101722948) retinoic acid receptor, alpha
  • cow(534280) retinoic acid receptor, alpha

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Small Molecule - Activator

Product Number
Description
Species
R4643
9-cis-Retinoic acid, ≥98% (HPLC),
Species
human
R2625
Retinoic acid, ≥98% (HPLC), powder,
Species
mouse, human

Small Molecule - Agonist

Product Number
Description
Species
A8843
AM580, ≥98% (HPLC),
Species
human
PHR1187
Tretinoin, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
1353500
Isotretinoin, United States Pharmacopeia (USP) Reference Standard,
Species
human
PHR1188
Isotretinoin, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
1674004
Tretinoin, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
A8843
AM580, ≥98% (HPLC),
Species
human
C5865
CD437, ≥98% (HPLC), solid,
Species
human
T3757
TTNPB, ,
Species
human
R2625
Retinoic acid, ≥98% (HPLC), powder,
Species
mouse, human

Antibodies

Product Number
Description
Species Reactivity
Application
WH0005914M1
Monoclonal Anti-RARA antibody produced in mouse, clone 2C9-1F8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB4504659
Anti-phospho-Retinoic Acid Receptor α (pSer77) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
SAB4502580
Anti-Retinoic Acid Receptor α antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
MAB5346
Anti-RAR alpha Antibody, clone 76, clone 763, Chemicon®, from mouse,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
SAB1411972
ANTI-RARA antibody produced in mouse, clone 1C10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
proximity ligation assay
western blot

Small Molecule - Ligand

Product Number
Description
Species
T3757
TTNPB, ,
Species
human
R4643
9-cis-Retinoic acid, ≥98% (HPLC),
Species
human
R2625
Retinoic acid, ≥98% (HPLC), powder,
Species
mouse, human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
R2625
Retinoic acid, ≥98% (HPLC), powder,
Species
mouse, human