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Merck

PTK6

protein tyrosine kinase 6

Synonyms:
BRK
Species:
UniProtKB ID:
Gene ID:
  • Human(5753) Summary: The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
  • Mouse(20459) PTK6 protein tyrosine kinase 6
  • Rat(366275) protein tyrosine kinase 6
  • domestic cat(101100294) PTK6 protein tyrosine kinase 6
  • Horse(100060532) PTK6 protein tyrosine kinase 6
  • cow(529814) PTK6 protein tyrosine kinase 6
  • sheep(101109378) PTK6 protein tyrosine kinase 6
  • naked mole-rat(101722381) protein tyrosine kinase 6
  • domestic guinea pig(100731622) protein tyrosine kinase 6

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-Brk (Tyr342) Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot
Anti-Brk Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
BRK, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
Brk Protein, active, 10 µg, ,
Species
human