PDX1
pancreatic and duodenal homeobox 1
Synonyms:
GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1
Species:
Human PDX1 (3651), Mouse Pdx1 (18609), Rat Pdx1 (29535), cow PDX1 (538927), sheep PDX1 (100820739), naked mole-rat Pdx1 (101715013), domestic guinea pig Pdx1 (100731776), Zebrafish pdx1 (30721), chicken PDX1 (771348), dog PDX1 (493994)
UniProtKB ID:
Gene ID:
- Human(3651) Summary: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Jul 2008]
- Mouse(18609) pancreatic and duodenal homeobox 1
- Rat(29535) pancreatic and duodenal homeobox 1
- cow(538927) pancreatic and duodenal homeobox 1
- sheep(100820739) pancreatic and duodenal homeobox 1
- naked mole-rat(101715013) pancreatic and duodenal homeobox 1
- domestic guinea pig(100731776) pancreatic and duodenal homeobox 1
- Zebrafish(30721) pancreatic and duodenal homeobox 1
- chicken(771348) pancreatic and duodenal homeobox 1
- dog(493994) pancreatic and duodenal homeobox 1
- domestic cat(100240682) pancreatic and duodenal homeobox 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PDX1 (goat) Antibody, serum, from goat,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot