PCSK6
proprotein convertase subtilisin/kexin type 6
Synonyms:
PACE4, SPC4
Species:
Human PCSK6 (5046), Mouse Pcsk6 (18553), Rat Pcsk6 (25507), chicken PCSK6 (395454), dog PCSK6 (488703), Horse PCSK6 (100057677), domestic cat PCSK6 (101083941), domestic guinea pig Pcsk6 (100716755), naked mole-rat Pcsk6 (101721857), Domestic Rabbit PCSK6 (100347173) ...More
UniProtKB ID:
Gene ID:
- Human(5046) Summary: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Mouse(18553) proprotein convertase subtilisin/kexin type 6
- Rat(25507) proprotein convertase subtilisin/kexin type 6
- chicken(395454) proprotein convertase subtilisin/kexin type 6
- dog(488703) proprotein convertase subtilisin/kexin type 6
- Horse(100057677) proprotein convertase subtilisin/kexin type 6
- domestic cat(101083941) proprotein convertase subtilisin/kexin type 6
- domestic guinea pig(100716755) proprotein convertase subtilisin/kexin type 6
- naked mole-rat(101721857) proprotein convertase subtilisin/kexin type 6
- Domestic Rabbit(100347173) proprotein convertase subtilisin/kexin type 6
- cow(524684) proprotein convertase subtilisin/kexin type 6
- sheep(101112091) proprotein convertase subtilisin/kexin type 6
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