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Merck

NTRK2

neurotrophic tyrosine kinase, receptor, type 2

Synonyms:
GP145-TrkB, TRKB, trk-B
Species:
Human NTRK2 (4915), Mouse Ntrk2 (18212), Rat Ntrk2 (25054), sheep NTRK2 (101116015), Domestic Rabbit NTRK2 (100352548), naked mole-rat Ntrk2 (101720037), domestic guinea pig Ntrk2 (100723565), chicken NTRK2 (396157), cow NTRK2 (505824), Horse NTRK2 (100061700) ...More
UniProtKB ID:
Q16620, B1ANZ4, B4DFV9, Q16675, Q59GJ1, Q8WXJ5, Q8WXJ6, Q8WXJ7
Gene ID:
  • Human(4915) Summary: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(18212) neurotrophic tyrosine kinase, receptor, type 2
  • Rat(25054) neurotrophic tyrosine kinase, receptor, type 2
  • sheep(101116015) neurotrophic tyrosine kinase, receptor, type 2
  • Domestic Rabbit(100352548) neurotrophic tyrosine kinase, receptor, type 2
  • naked mole-rat(101720037) neurotrophic tyrosine kinase, receptor, type 2
  • domestic guinea pig(100723565) neurotrophic tyrosine kinase, receptor, type 2
  • chicken(396157) neurotrophic tyrosine kinase, receptor, type 2
  • cow(505824) neurotrophic tyrosine kinase, receptor, type 2
  • Horse(100061700) neurotrophic tyrosine kinase, receptor, type 2
  • domestic cat(101101347) neurotrophic tyrosine kinase, receptor, type 2
  • dog(484147) neurotrophic tyrosine kinase, receptor, type 2

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB4300256
Anti-phospho-NTRK2 (pTyr705) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
AB9872
Anti-TrkB Antibody, serum, Chemicon®,
Species Reactivity
mouse, rat
Application
immunohistochemistry
AB5372
Anti-Trk B Antibody, pain, a.a. 54-67 rTrkB, serum, Chemicon®,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
SAB4300255
Anti-phospho-NTRK2 (pTyr515) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
SAB4503786
Anti-phospho-Trk B (pTyr705) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
T8694
TrkB/Fc Chimera human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
human
14-507-M
TrkB Recombinant Human Protein, Active, 10 µg, Active, N-terminal His6 tagged, recombinant, human TrkB, amino acids 455-end, for use in Kinase Assays.,
Species
human