NDUFV1
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
Synonyms:
CI-51K, CI51KD, UQOR1
Species:
Human NDUFV1 (4723), Mouse Ndufv1 (17995), Rat Ndufv1 (293655), Zebrafish ndufv1 (445291), chicken NDUFV1 (430210), dog NDUFV1 (476004), cow NDUFV1 (287014), domestic cat NDUFV1 (101093395), sheep NDUFV1 (101121129), naked mole-rat Ndufv1 (101726275)
UniProtKB ID:
Gene ID:
- Human(4723) Summary: The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]
- Mouse(17995) NADH dehydrogenase (ubiquinone) flavoprotein 1
- Rat(293655) NADH dehydrogenase (ubiquinone) flavoprotein 1
- Zebrafish(445291) NADH dehydrogenase (ubiquinone) flavoprotein 1
- chicken(430210) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- dog(476004) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- cow(287014) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- domestic cat(101093395) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- sheep(101121129) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- naked mole-rat(101726275) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- domestic guinea pig(100725831) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-NDUFV1 antibody produced in mouse, clone 4A7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Metformin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human