NAE1
NEDD8 activating enzyme E1 subunit 1
Synonyms:
A-116A10.1, APPBP1, ula-1
Species:
Human NAE1 (8883), Mouse Nae1 (234664), Rat Nae1 (84019), naked mole-rat Nae1 (101700870), Domestic Rabbit NAE1 (100350243), domestic guinea pig Nae1 (100725751), sheep NAE1 (101108941), Zebrafish nae1 (573336), chicken NAE1 (415792), chicken NAE1 (776979) ...More
UniProtKB ID:
Gene ID:
- Human(8883) Summary: The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(234664) NEDD8 activating enzyme E1 subunit 1
- Rat(84019) NEDD8 activating enzyme E1 subunit 1
- naked mole-rat(101700870) NEDD8 activating enzyme E1 subunit 1
- Domestic Rabbit(100350243) NEDD8 activating enzyme E1 subunit 1
- domestic guinea pig(100725751) NEDD8 activating enzyme E1 subunit 1
- sheep(101108941) NEDD8 activating enzyme E1 subunit 1
- Zebrafish(573336) nedd8 activating enzyme E1 subunit 1
- chicken(415792) NEDD8 activating enzyme E1 subunit 1
- chicken(776979) NEDD8 activating enzyme E1 subunit 1
- cow(614491) NEDD8 activating enzyme E1 subunit 1
- Horse(100065540) NEDD8 activating enzyme E1 subunit 1
- domestic cat(101086523) NEDD8 activating enzyme E1 subunit 1
- dog(610026) NEDD8 activating enzyme E1 subunit 1
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