MXI1
MAX interactor 1, dimerization protein
Synonyms:
MAD2, MXD2, MXI, bHLHc11
Species:
Human MXI1 (4601), Mouse Mxi1 (17859), Rat Mxi1 (25701), Zebrafish mxi1 (30485), dog MXI1 (609946), chicken MXI1 (423888), domestic cat MXI1 (101092646), cow MXI1 (614509), domestic guinea pig Mxi1 (100733154), naked mole-rat Mxi1 (101697683)
UniProtKB ID:
Gene ID:
- Human(4601) Summary: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq, Jul 2008]
- Mouse(17859) Max interacting protein 1
- Rat(25701) MAX interactor 1
- Zebrafish(30485) max interacting protein
- dog(609946) MAX interactor 1
- chicken(423888) MAX interactor 1
- domestic cat(101092646) MAX interactor 1
- cow(614509) MAX interactor 1
- domestic guinea pig(100733154) MAX interactor 1, dimerization protein
- naked mole-rat(101697683) MAX interactor 1, dimerization protein
- sheep(101118067) MAX interactor 1, dimerization protein
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MXI1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot