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Merck

MST1R

macrophage stimulating 1 receptor (c-met-related tyrosine kinase)

Synonyms:
CD136, CDw136, PTK8, RON
Species:
UniProtKB ID:
Gene ID:
  • Human(4486) Summary: This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternatively spliced transcript variants encoding different isoforms with different structural and biochemical properties have been described (PMID:8816464). [provided by RefSeq, Oct 2011]
  • Mouse(19882) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • Rat(300999) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • chicken(427573) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • domestic cat(101089993) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • cow(525504) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • Horse(100062492) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • dog(444854) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • sheep(101116433) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • naked mole-rat(101720807) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • domestic guinea pig(100732415) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-CD136/RON (pSer1394) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot