MGST1
microsomal glutathione S-transferase 1
Synonyms:
GST12, MGST, MGST-I
Species:
Human MGST1 (4257), Mouse Mgst1 (56615), Rat Mgst1 (171341), Zebrafish mgst1 (449784), chicken MGST1 (418178), dog MGST1 (477683), cow MGST1 (493719), domestic cat MGST1 (101099565), naked mole-rat Mgst1 (101713569), domestic guinea pig Mgst1 (100736210)
UniProtKB ID:
Gene ID:
- Human(4257) Summary: The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene. [provided by RefSeq, May 2012]
- Mouse(56615) microsomal glutathione S-transferase 1
- Rat(171341) microsomal glutathione S-transferase 1
- Zebrafish(449784) microsomal glutathione S-transferase 1
- chicken(418178) microsomal glutathione S-transferase 1
- dog(477683) microsomal glutathione S-transferase 1
- cow(493719) microsomal glutathione S-transferase 1
- domestic cat(101099565) microsomal glutathione S-transferase 1
- naked mole-rat(101713569) microsomal glutathione S-transferase 1
- domestic guinea pig(100736210) microsomal glutathione S-transferase 1
- sheep(101103462) microsomal glutathione S-transferase 1
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