MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
Synonyms:
IB2, JIP2, PRKM8IPL
Species:
Human MAPK8IP2 (23542), Mouse Mapk8ip2 (60597), Rat Mapk8ip2 (315220), naked mole-rat Mapk8ip2 (101712713), domestic guinea pig Mapk8ip2 (100724140), sheep MAPK8IP2 (101119037), Zebrafish mapk8ip2 (561262), dog MAPK8IP2 (481183), domestic cat MAPK8IP2 (101085733), cow MAPK8IP2 (618893)
UniProtKB ID:
Gene ID:
- Human(23542) Summary: The protein encoded by this gene is closely related to MAPK8IP1/IB1/JIP-1, a scaffold protein that is involved in the c-Jun amino-terminal kinase signaling pathway. This protein is expressed in brain and pancreatic cells. It has been shown to interact with, and regulate the activity of MAPK8/JNK1, and MAP2K7/MKK7 kinases. This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008]
- Mouse(60597) mitogen-activated protein kinase 8 interacting protein 2
- Rat(315220) mitogen-activated protein kinase 8 interacting protein 2
- naked mole-rat(101712713) mitogen-activated protein kinase 8 interacting protein 2
- domestic guinea pig(100724140) mitogen-activated protein kinase 8 interacting protein 2
- sheep(101119037) mitogen-activated protein kinase 8 interacting protein 2
- Zebrafish(561262) mitogen-activated protein kinase 8 interacting protein 2
- dog(481183) mitogen-activated protein kinase 8 interacting protein 2
- domestic cat(101085733) mitogen-activated protein kinase 8 interacting protein 2
- cow(618893) mitogen-activated protein kinase 8 interacting protein 2
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