IL1B
interleukin 1, beta
Synonyms:
IL-1, IL1-BETA, IL1F2
Species:
Human IL1B (3553), Mouse Il1b (16176), Rat Il1b (24494), Zebrafish il1b (557541), domestic cat IL1B (768274), cow IL1B (281251), Horse IL1B (100034237), dog IL1B (403974), Zebrafish il1b (405770), chicken IL1B (395196) ...More
UniProtKB ID:
Gene ID:
- Human(3553) Summary: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
- Mouse(16176) interleukin 1 beta
- Rat(24494) interleukin 1 beta
- Zebrafish(557541) interleukin 1, beta
- domestic cat(768274) interleukin 1, beta
- cow(281251) interleukin 1, beta
- Horse(100034237) interleukin 1, beta
- dog(403974) interleukin 1, beta
- Zebrafish(405770) interleukin 1, beta
- chicken(395196) interleukin 1, beta
- Goat(100860816) interleukin 1, beta
- Domestic Rabbit(100008990) interleukin 1, beta
- domestic guinea pig(100135556) interleukin 1 beta
- naked mole-rat(101704309) interleukin 1, beta
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ELISA
Product Number
Description
Species
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Interleukin-1β Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
ELISA
neutralization
western blot
neutralization
western blot
Monoclonal Anti-Interleukin-1β antibody produced in mouse, clone 8516.311, purified immunoglobulin, lyophilized powder,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry
neutralization
western blot
immunohistochemistry
neutralization
western blot
Anti-Interleukin-1 beta (IL-1B) Antibody, clone 4A7, clone AB34_41.4H12.4A7, from mouse,
Species Reactivity
human
Application
western blot
Monoclonal Anti-IL1B antibody produced in mouse, clone 2A8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunoprecipitation (IP)
western blot
immunofluorescence
immunoprecipitation (IP)
western blot
Anti-IL1B antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
Interleukin-1β from mouse, IL-1β, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
mouse
Interleukin-1β from rat, IL-1β, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
rat
Interleukin-1β human, IL-1β, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture, endotoxin tested,
Species
human
IL-1 beta human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human
esiRNA
Product Number
Description
Species