Skip to Content
Merck

IGFBP3

insulin-like growth factor binding protein 3

Synonyms:
BP-53, IBP3
Species:
Human IGFBP3 (3486), Mouse Igfbp3 (16009), Rat Igfbp3 (24484), Zebrafish igfbp3 (403079), chicken IGFBP3 (420790), dog IGFBP3 (491618), domestic cat IGFBP3 (101080442), cow IGFBP3 (282261), sheep IGFBP3 (100286737), domestic guinea pig Igfbp3 (100714097)
UniProtKB ID:
P17936, A4D2F5, D3DVM0, Q2V509, Q6P1M6, Q9UCL4
Gene ID:
  • Human(3486) Summary: This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(16009) insulin-like growth factor binding protein 3
  • Rat(24484) insulin-like growth factor binding protein 3
  • Zebrafish(403079) insulin-like growth factor binding protein 3
  • chicken(420790) insulin-like growth factor binding protein 3
  • dog(491618) insulin-like growth factor binding protein 3
  • domestic cat(101080442) insulin-like growth factor binding protein 3
  • cow(282261) insulin-like growth factor binding protein 3
  • sheep(100286737) insulin-like growth factor binding protein 3
  • domestic guinea pig(100714097) insulin-like growth factor binding protein 3
  • naked mole-rat(101710997) insulin-like growth factor binding protein 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
SAB1300411
Anti-IGFBP3 (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
SAB1410698
Anti-IGFBP3 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot

Proteins

Product Number
Description
Species
I5278
Insulin-Like Growth Factor Binding Protein-3 human, recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture, ≥95% (SDS-PAGE),
Species
human
SRP3067
IGF-Binding Protein-3 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human