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Merck

GABRG3

gamma-aminobutyric acid (GABA) A receptor, gamma 3

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(2567) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
  • Mouse(14407) gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
  • Rat(79211) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • domestic guinea pig(100729690) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • naked mole-rat(101712623) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • sheep(101108521) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • Zebrafish(567057) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • cow(613670) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • domestic cat(101094182) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • dog(488685) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • chicken(770097) gamma-aminobutyric acid (GABA) A receptor, gamma 3

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Small Molecule - Agonist

Product Number
Description
Species
Meprobamate, analytical standard,
Species
human
Oxazepam, ,
Species
human
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
Clonazepam, European Pharmacopoeia (EP) Reference Standard,
Species
human
Pentobarbital, United States Pharmacopeia (USP) Reference Standard,
Species
human
Diazepam, United States Pharmacopeia (USP) Reference Standard,
Species
human
Clorazepate dipotassium, United States Pharmacopeia (USP) Reference Standard,
Species
human
Butalbital, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Species
human
Flunitrazepam, ,
Species
human
Clonazepam, powder,
Species
human, rat
Ganaxolone, ≥98% (HPLC), solid,
Species
human, mouse
Diazepam, ,
Species
human, rat