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Merck

FZD7

frizzled family receptor 7

Synonyms:
FzE3
Species:
UniProtKB ID:
Gene ID:
  • Human(8324) Summary: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]
  • Mouse(14369) frizzled homolog 7 (Drosophila)
  • Rat(301440) frizzled family receptor 7
  • sheep(101103546) frizzled family receptor 7
  • domestic guinea pig(100735394) frizzled family receptor 7
  • naked mole-rat(101704351) frizzled family receptor 7
  • chicken(374060) frizzled family receptor 7
  • cow(524255) frizzled family receptor 7
  • domestic cat(101087255) frizzled family receptor 7
  • dog(488478) frizzled family receptor 7

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FZD7 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence

western blot
Anti-Frizzled-7 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot