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Merck

FLG

filaggrin

Synonyms:
ATOD2
Species:
UniProtKB ID:
Gene ID:
  • Human(2312) Summary: The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.[provided by RefSeq, Dec 2009]
  • Mouse(14246) filaggrin
  • Rat(24641) filaggrin
  • cow(788551) filaggrin
  • naked mole-rat(101699480) filaggrin
  • domestic guinea pig(100728006) filaggrin

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FLG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry