FGF20
fibroblast growth factor 20
Synonyms:
FGF-20
Species:
Human FGF20 (26281), Mouse Fgf20 (80857), Rat Fgf20 (66017), domestic guinea pig Fgf20 (100732836), naked mole-rat Fgf20 (101701734), sheep FGF20 (101121489), chicken FGF20 (428779), dog FGF20 (606908), cow FGF20 (539083), domestic cat FGF20 (101083766)
UniProtKB ID:
Gene ID:
- Human(26281) Summary: The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility. [provided by RefSeq, Oct 2009]
- Mouse(80857) fibroblast growth factor 20
- Rat(66017) fibroblast growth factor 20
- domestic guinea pig(100732836) fibroblast growth factor 20
- naked mole-rat(101701734) fibroblast growth factor 20
- sheep(101121489) fibroblast growth factor 20
- chicken(428779) fibroblast growth factor 20
- dog(606908) fibroblast growth factor 20
- cow(539083) fibroblast growth factor 20
- domestic cat(101083766) fibroblast growth factor 20
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