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Merck

CLDN7

claudin 7

Synonyms:
CEPTRL2, CLDN-7, CPETRL2, Hs.84359, claudin-1
Species:
UniProtKB ID:
Gene ID:
  • Human(1366) Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010]
  • Mouse(53624) claudin 7
  • Rat(65132) claudin 7
  • sheep(100462658) claudin 7
  • domestic guinea pig(100716900) claudin 7
  • naked mole-rat(101713277) claudin 7
  • cow(512975) claudin 7
  • dog(489466) claudin 7
  • domestic cat(101096019) claudin 7

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Claudin 7 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-Claudin-7 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat
Application
western blot