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Merck

CFP

complement factor properdin

Synonyms:
BFD, PFC, PFD, PROPERDIN
Species:
Human CFP (5199), Mouse Cfp (18636), Rat Cfp (299314), Zebrafish cfp (556399), dog CFP (491859), domestic cat CFP (101090086), cow CFP (539605), Horse CFP (100051317), naked mole-rat Cfp (101724230), domestic guinea pig Cfp (100728194) ...More
UniProtKB ID:
P27918, O15134, O15135, O15136, O75826
Gene ID:
  • Human(5199) Summary: This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Feb 2009]
  • Mouse(18636) complement factor properdin
  • Rat(299314) complement factor properdin
  • Zebrafish(556399) complement factor properdin
  • dog(491859) complement factor properdin
  • domestic cat(101090086) complement factor properdin
  • cow(539605) complement factor properdin
  • Horse(100051317) complement factor properdin
  • naked mole-rat(101724230) complement factor properdin
  • domestic guinea pig(100728194) complement factor properdin
  • sheep(101114678) complement factor properdin
  • Domestic Rabbit(100340696) complement factor properdin

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2108322
Anti-CFP antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot