CES1
carboxylesterase 1
Synonyms:
ACAT, CE-1, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, hCE-1
Species:
Human CES1 (1066), chicken CES1 (415786), cow CES1 (512098), domestic cat CES1 (493774), dog CES1 (403643), naked mole-rat Ces1 (101726140)
UniProtKB ID:
Gene ID:
- Human(1066) Summary: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
- chicken(415786) carboxylesterase 1 (monocyte/macrophage serine esterase 1)
- cow(512098) carboxylesterase 1 (monocyte/macrophage serine esterase 1)
- domestic cat(493774) carboxylesterase 1
- dog(403643) carboxylesterase 1
- naked mole-rat(101726140) carboxylesterase 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CES1 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
western blot
Anti-CES1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot