CD8B
CD8b molecule
Synonyms:
CD8B1, LEU2, LY3, LYT3, P37
Species:
Human CD8B (926), Rat Cd8b (24931), sheep CD8B (101103712), domestic guinea pig Cd8b (100379572), naked mole-rat Cd8b (101720046), chicken CD8B (396175), dog CD8B (483076), cow CD8B (508633), domestic cat CD8B (493948)
UniProtKB ID:
Gene ID:
- Human(926) Summary: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010]
- Rat(24931) CD8b molecule
- sheep(101103712) CD8b molecule
- domestic guinea pig(100379572) CD8b molecule
- naked mole-rat(101720046) CD8b molecule
- chicken(396175) CD8b molecule
- dog(483076) CD8b molecule
- cow(508633) CD8b molecule
- domestic cat(493948) CD8b molecule
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD8 antibody produced in mouse, clone UCHT-4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Monoclonal Anti-CD8−FITC antibody produced in mouse, clone UCHT-4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry