CASP8AP2
caspase 8 associated protein 2
Synonyms:
CED-4, FLASH, RIP25
Species:
Human CASP8AP2 (9994), Mouse Casp8ap2 (26885), Rat Casp8ap2 (313128), Zebrafish casp8ap2 (541521), cow CASP8AP2 (505138), Horse CASP8AP2 (100065766), domestic cat CASP8AP2 (101095416), dog CASP8AP2 (481921), chicken CASP8AP2 (421810), sheep CASP8AP2 (101109100) ...More
UniProtKB ID:
Gene ID:
- Human(9994) Summary: This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008]
- Mouse(26885) caspase 8 associated protein 2
- Rat(313128) caspase 8 associated protein 2
- Zebrafish(541521) CASP8 associated protein 2
- cow(505138) caspase 8 associated protein 2
- Horse(100065766) caspase 8 associated protein 2
- domestic cat(101095416) caspase 8 associated protein 2
- dog(481921) caspase 8 associated protein 2
- chicken(421810) caspase 8 associated protein 2
- sheep(101109100) caspase 8 associated protein 2
- Domestic Rabbit(100342805) caspase 8 associated protein 2
- naked mole-rat(101700716) caspase 8 associated protein 2
- domestic guinea pig(100729800) caspase 8 associated protein 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-FLASH antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-CASP8AP2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Small Molecule - Substrate
Product Number
Description
Species
N-Acetyl-Ile-Glu-Thr-Asp-7-Amido-4-methylcoumarin, ≥97% (HPLC), powder,
Species
rat, mouse, human
N-Acetyl-Ile-Glu-Pro-Asp-7-amido-4-methylcoumarin, ≥97% (HPLC), powder,
Species
rat, mouse, human