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Merck

ATP4A

ATPase, H+/K+ exchanging, alpha polypeptide

Synonyms:
ATP6A
Species:
UniProtKB ID:
Gene ID:
  • Human(495) Summary: The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes a catalytic alpha subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008]
  • Mouse(11944) ATPase, H+/K+ exchanging, gastric, alpha polypeptide
  • Rat(24216) ATPase, H+/K+ exchanging, alpha polypeptide
  • dog(431686) ATPase, H+/K+ exchanging, alpha polypeptide
  • cow(521163) ATPase, H+/K+ exchanging, alpha polypeptide
  • domestic cat(101100771) ATPase, H+/K+ exchanging, alpha polypeptide
  • naked mole-rat(101724247) ATPase, H+/K+ exchanging, alpha polypeptide
  • domestic guinea pig(100732743) ATPase, H+/K+ exchanging, alpha polypeptide
  • sheep(101116166) ATPase, H+/K+ exchanging, alpha polypeptide
  • Domestic Rabbit(100009279) ATPase, H+/K+ exchanging, alpha polypeptide

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Small Molecule - Inhibitor

Product Number
Description
Species
Lansoprazole, ≥98% (TLC), powder,
Species
human
Lansoprazole, British Pharmacopoeia (BP) Reference Standard,
Species
human
Rabeprazole sodium, ≥98% (HPLC),
Species
human
Lansoprazole, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Lansoprazole, European Pharmacopoeia (EP) Reference Standard,
Species
human