ASGR1
asialoglycoprotein receptor 1
ASGPR, ASGPR1, CLEC4H1, HL-1
Human ASGR1 (432), Mouse Asgr1 (11889), Rat Asgr1 (24210), dog ASGR1 (489461), cow ASGR1 (509121), naked mole-rat Asgr1 (101707146), domestic guinea pig Asgr1 (100714188), sheep ASGR1 (101116157)
- Human(432) Summary: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
- Mouse(11889) asialoglycoprotein receptor 1
- Rat(24210) asialoglycoprotein receptor 1
- dog(489461) asialoglycoprotein receptor 1
- cow(509121) asialoglycoprotein receptor 1
- naked mole-rat(101707146) asialoglycoprotein receptor 1
- domestic guinea pig(100714188) asialoglycoprotein receptor 1
- sheep(101116157) asialoglycoprotein receptor 1
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