ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
Synonyms:
GEFT, p63RhoGEF
Species:
Human ARHGEF25 (115557), Mouse Arhgef25 (52666), Rat Arhgef25 (314904), sheep ARHGEF25 (101118430), Domestic Rabbit ARHGEF25 (100339852), naked mole-rat Arhgef25 (101710520), domestic guinea pig Arhgef25 (100719628), dog ARHGEF25 (607485), domestic cat ARHGEF25 (101095589), cow ARHGEF25 (506075)
UniProtKB ID:
Gene ID:
- Human(115557) Summary: Rho GTPases alternate between an inactive GDP-bound state and an active GTP-bound state, and GEFs facilitate GDP/GTP exchange. This gene encodes a guanine nucleotide exchange factor (GEF) which interacts with Rho GTPases involved in contraction of vascular smooth muscles, regulation of responses to angiotensin II and lens cell differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
- Mouse(52666) Rho guanine nucleotide exchange factor (GEF) 25
- Rat(314904) Rho guanine nucleotide exchange factor (GEF) 25
- sheep(101118430) Rho guanine nucleotide exchange factor (GEF) 25
- Domestic Rabbit(100339852) Rho guanine nucleotide exchange factor (GEF) 25
- naked mole-rat(101710520) Rho guanine nucleotide exchange factor (GEF) 25
- domestic guinea pig(100719628) Rho guanine nucleotide exchange factor (GEF) 25
- dog(607485) Rho guanine nucleotide exchange factor (GEF) 25
- domestic cat(101095589) Rho guanine nucleotide exchange factor (GEF) 25
- cow(506075) Rho guanine nucleotide exchange factor (GEF) 25
- Horse(100050699) Rho guanine nucleotide exchange factor (GEF) 25
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