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Merck

APOC2

apolipoprotein C-II

Synonyms:
APO-CII, APOC-II
Species:
UniProtKB ID:
Gene ID:
  • Human(344) Summary: This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene. [provided by RefSeq, Mar 2011]
  • Mouse(11813) apolipoprotein C-II
  • Rat(292697) apolipoprotein C-II
  • Zebrafish(568972) apolipoprotein C-II
  • cow(618039) apolipoprotein C-II
  • domestic cat(101096861) apolipoprotein C-II
  • dog(442969) apolipoprotein C-II
  • domestic guinea pig(100135480) apolipoprotein C-II
  • sheep(101112082) apolipoprotein C-II

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-APOC2, (C-terminal) antibody produced in mouse, clone 3E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

Proteins

Product Number
Description
Species
Apolipoprotein C-II from human plasma, ≥95% (SDS-PAGE),
Species
human
Lipoprotein, high density from human plasma, ≥95% (SDS-PAGE), solution,
Species
human
Lipoprotein, low density from human plasma, ≥95% (SDS-PAGE), solution,
Species
human