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Merck

ABCB6

ATP-binding cassette, sub-family B (MDR/TAP), member 6

Synonyms:
ABC, ABC14, DUH3, LAN, MCOPCB7, MTABC3, PRP, umat
Species:
Human ABCB6 (10058), Mouse Abcb6 (74104), Rat Abcb6 (140669), chicken ABCB6 (425721), cow ABCB6 (783257), Horse ABCB6 (100059171), domestic cat ABCB6 (101094528), naked mole-rat Abcb6 (101723206), domestic guinea pig Abcb6 (100722513), Goat ABCB6 (100861157)
UniProtKB ID:
Q9NP58, O75542, Q49A66, Q59GQ5, Q6ZME6, Q96ME8, Q9HAQ6, Q9HAQ7
Gene ID:
  • Human(10058) Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function. [provided by RefSeq, Jul 2008]
  • Mouse(74104) ATP-binding cassette, sub-family B (MDR/TAP), member 6
  • Rat(140669) ATP-binding cassette, subfamily B (MDR/TAP), member 6
  • chicken(425721) ATP-binding cassette, sub-family B (MDR/TAP), member 6
  • cow(783257) ATP-binding cassette, sub-family B (MDR/TAP), member 6
  • Horse(100059171) ATP-binding cassette, sub-family B (MDR/TAP), member 6
  • domestic cat(101094528) ATP-binding cassette, sub-family B (MDR/TAP), member 6
  • naked mole-rat(101723206) ATP-binding cassette, sub-family B (MDR/TAP), member 6
  • domestic guinea pig(100722513) ATP-binding cassette, sub-family B (MDR/TAP), member 6
  • Goat(100861157) ATP-binding cassette, sub-family B (MDR/TAP), member 6
  • sheep(101115097) ATP-binding cassette, sub-family B (MDR/TAP), member 6

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB1300078
Anti-ABCB6 (C-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot