Determination of volatile organic compounds including alcohols in refill fluids and cartridges of electronic cigarettes by headspace solid-phase micro extraction and gas chromatography-mass spectrometry.

Determination of volatile organic compounds including alcohols in refill fluids and cartridges of electronic cigarettes by headspace solid-phase micro extraction and gas chromatography-mass spectrometry.

Analytical and bioanalytical chemistry (2016-11-09)

Hyun-Hee Lim, Ho-Sang Shin

ABSTRACT

An analytical method for the detection of 14 volatile organic compounds (VOCs) was developed to investigate VOCs in refill fluids and cartridges of electronic cigarettes (EC) using headspace solid-phase micro extraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS). In total, 14 VOCs were identified and quantified in 283 flavored liquids, 21 nicotine liquids, and 12 disposable cartridges. The detected concentration ranges of the VOCs are as follows: benzene (0.008-2.28 mg L

MATERIALS

Product Number

Brand

Product Description

57310-U

Supelco

SPME Fiber Assembly Polydimethylsiloxane/Divinylbenzene (PDMS/DVB), d_f 65 μm(PDMS/DVB, needle size 24 ga, for use with manual holder

57345-U

Supelco

SPME Fiber Assembly Polydimethylsiloxane/Divinylbenzene (PDMS/DVB), d_f 65 μm(PDMS/DVB, for use with autosampler, needle size 23 ga

57362-U

Supelco

SPME fiber assortment kit 5, needle size 23 ga, for use with autosampler

57325-U

Supelco

SPME fiber assortment kit 4, for use with autosampler, size 24 ga

57287-U

Supelco

SPME fiber assortment kit 4, for use with autosampler, needle size 23 ga

57285-U

Supelco

SPME fiber assortment kit 1, for use with autosampler, needle size 23 ga

57286-U

Supelco

SPME fiber assortment kit 2, for use with autosampler, needle size 23 ga

57346-U

Supelco

SPME Fiber Assembly Polydimethylsiloxane/Divinylbenzene (PDMS/DVB), d_f 65 μm(PDMS/DVB, fused silica fiber, for use with manual holder, needle size 23 ga

57550-U

Supelco

SPME StableFlex^™ fiber assortment kit, for use with manual holder

57324-U

Supelco

SPME fiber assortment kit 4, for use with manual holder, size 24 ga

57327-U

Supelco

SPME Fiber Assembly Polydimethylsiloxane/Divinylbenzene (PDMS/DVB), d_f 65 μm(PDMS/DVB, needle size 24 ga, StableFlex, for use with autosampler

57321-U

Supelco

SPME fiber assortment kit 2, for use with autosampler, size 24 ga

57320-U

Supelco

SPME fiber assortment kit 2, for use with manual holder, needle size 24 ga

57354-U

Supelco

SPME fiber assembly, Carbowax-Polyethylene Glycol (PEG) Coating, needle size 23 ga, d_f 60 μm(PEG, for use with autosampler

57551-U

Supelco

SPME StableFlex^™ fiber assortment kit, for use with autosampler, needle size 24 ga

57293-U

Supelco

SPME Fiber Assembly Polydimethylsiloxane/Divinylbenzene (PDMS/DVB), d_f 65 μm(PDMS/DVB, needle size 23 ga, PDMS/DVB StableFlex, for use with autosampler

W312606

Sigma-Aldrich

2-Acetylpyrazine, ≥99%, FCC, FG

235695

Sigma-Aldrich

Octamethylcyclotetrasiloxane, 98%

57307

Supelco

SPME fiber assortment kit 1, for use with autosampler, needle size 24 ga

57306

Supelco

SPME fiber assortment kit 1, for use with manual holder, needle size 24 ga

57311

Supelco

SPME Fiber Assembly Polydimethylsiloxane/Divinylbenzene (PDMS/DVB), d_f 65 μm(PDMS/DVB, needle size 24 ga, for use with autosampler