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PHR1469

Supelco

Hydroquinone

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Hydroquinone, 1,4-Benzenediol, 1,4-Dihydroxybenzene, HQ

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About This Item

Linear Formula:
C6H4-1,4-(OH)2
CAS Number:
123-31-9
Molecular Weight:
110.11
Beilstein:
605970
EC Number:
204-617-8
MDL number:
MFCD00002339
UNSPSC Code:
41116107
PubChem Substance ID:
329823399
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to USP 1324002

vapor density

3.81 (vs air)

vapor pressure

1 mmHg ( 132 °C)

API family

hydroquinone

CofA

current certificate can be downloaded

autoignition temp.

930 °F

packaging

pkg of 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

285 °C (lit.)

mp

172-175 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

Oc1ccc(O)cc1

InChI

1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H

InChI key

QIGBRXMKCJKVMJ-UHFFFAOYSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Hydroquinone may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC) and spectrophotometry techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA3017 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1B

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LRAC9154
LRAC3211
LRAA9224
LRAA3017

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Automated flow-injection spectrophotometric determination of catecholamines (epinephrine and isoproterenol) in pharmaceutical formulations based on ferrous complex formation.
Solich P, et al.
Journal of Pharmaceutical and Biomedical Analysis, 22(5), 781-789 (2000)
Development and validation of a new RP-HPLC method for the simultaneous determination of hydroquinone, kojic acid, octinoxate, avobenzone, BHA and BHT in skin-whitening cream.
Galimany-Rovira F, et al.
Analytical Methods : Advancing Methods and Applications, 8(5), 1170-1180 (2016)
Thomas Kruse et al.
Journal of bacteriology, 197(5), 893-904 (2014-12-17)
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A seed's ability to properly germinate largely depends on its oxidative poise. The level of reactive oxygen species (ROS) in Arabidopsis (Arabidopsis thaliana) is controlled by a large gene network, which includes the gene coding for the hydrogen peroxide-scavenging enzyme
Richard T Penson et al.
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