SORT1
sortilin 1
Gp95, LDLCQ6, NT3
Human SORT1 (6272), Mouse Sort1 (20661), Rat Sort1 (83576), cow SORT1 (511591), sheep SORT1 (101104538), naked mole-rat Sort1 (101698000), domestic guinea pig Sort1 (100718269), chicken SORT1 (100858592), Horse SORT1 (100061385), domestic cat SORT1 (101090199)
- Human(6272) Summary: This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p; the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins. [provided by RefSeq, Jul 2008]
- Mouse(20661) sortilin 1
- Rat(83576) sortilin 1
- cow(511591) sortilin 1
- sheep(101104538) sortilin 1
- naked mole-rat(101698000) sortilin 1
- domestic guinea pig(100718269) sortilin 1
- chicken(100858592) sortilin 1
- Horse(100061385) sortilin 1
- domestic cat(101090199) sortilin 1
- dog(479915) sortilin 1
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ELISA
Antibodies
Anti-SORT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunohistochemistry
western blot
western blot
Anti-Sortilin Antibody, clone F11, clone F11, from mouse,
human, mouse
ELISA
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Monoclonal Anti-SORT1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL6528, purified immunoglobulin, buffered aqueous glycerol solution,
human, mouse
immunohistochemistry
western blot
western blot
Anti-Sortilin Antibody, clone 4E3.1, clone 4E3.1, from mouse,
human, mouse
immunohistochemistry
western blot
western blot