LIFR
leukemia inhibitory factor receptor alpha
Synonyms:
CD118, LIF-R, SJS2, STWS, SWS
Species:
Human LIFR (3977), Mouse Lifr (16880), Rat Lifr (81680), sheep LIFR (101106364), Domestic Rabbit LIFR (100303762), domestic guinea pig Lifr (100716454), naked mole-rat Lifr (101696861), chicken LIFR (395262), dog LIFR (449478), cow LIFR (539504)
UniProtKB ID:
Gene ID:
- Human(3977) Summary: This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(16880) leukemia inhibitory factor receptor
- Rat(81680) leukemia inhibitory factor receptor alpha
- sheep(101106364) leukemia inhibitory factor receptor alpha
- Domestic Rabbit(100303762) leukemia inhibitory factor receptor alpha
- domestic guinea pig(100716454) leukemia inhibitory factor receptor alpha
- naked mole-rat(101696861) leukemia inhibitory factor receptor alpha
- chicken(395262) leukemia inhibitory factor receptor alpha
- dog(449478) leukemia inhibitory factor receptor alpha
- cow(539504) leukemia inhibitory factor receptor alpha
- domestic cat(101097206) leukemia inhibitory factor receptor alpha
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-LIFR antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-LIF Receptor, clone 1C7 (Azide Free) Antibody, clone 1C7, from mouse,
Species Reactivity
human
Application
flow cytometry
inhibition assay
inhibition assay
Anti-Human LIF-R (1C7) ColorWheel® Dye-Ready mAb, ,
Species Reactivity
human
Application
flow cytometry
esiRNA
Product Number
Description
Species