Skip to Content
Merck

CXCL1

chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)

Synonyms:
FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1
Species:
UniProtKB ID:
Gene ID:
  • Human(2919) Summary: This gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signal through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Jan 2012]
  • Mouse(14825) chemokine (C-X-C motif) ligand 1
  • Rat(81503) chemokine (C-X-C motif) ligand 1
  • Horse(100034121) chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
  • sheep(443380) chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
  • domestic guinea pig(100135510) chemokine (C-X-C motif) ligand 1
  • naked mole-rat(101705558) chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
Human GRO-α / CXCL1 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Mouse KC / CXCL1 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse
Rat CINC-1 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CXCL1, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-CXCL1/GROa Antibody, clone HL2401, ,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)

inhibition assay

western blot
Monoclonal Anti-CXCL1 antibody produced in mouse, clone 2D7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA

Proteins

Product Number
Description
Species
KC (CXCL1) from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
mouse
GRO/KC from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Species
mouse
GRO/KC (CXCL1) from rat, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
rat
GROα human, ≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Cxcl1,
Species
mouse
MISSION® esiRNA, targeting human CXCL1,
Species
human